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Realising the potential of single-use technology – As published in Manufacturing Chemist

Posted on January 8, 2019 by Helena Rogers

In this article Zenith Technologies’ Global Director of Managed Services David Staunton and Scott Ripley, Global Marketing Director at GE Healthcare, discuss the benefits and patient impact of single-use technology with Manufacturing Chemist.

The GMP manufacturing adoption of single-use technologies is directly aligned with the need to increase productivity and provide flexible processing schemes that can adapt to the rapidly changing biopharmaceutical market needs.

The implementation of single-use technology in GMP manufacturing is growing rapidly. This is primarily because of the increased yields available using disposable technology, the growth of biosimilar approvals and the acceptance of personalised medicines.

Single-use equipment trains are also enabling innovative start-ups and contract manufacturers to rapidly produce clinical trial material, monoclonal antibodies (mAbs) or cell and gene therapies.

Benefits of a single-use implementation strategy

Both upstream and downstream manufacturing processes benefit from single-use systems. They allow manufacturers to quickly add capacity at lower costs. They also make multiproduct GMP manufacturing easier to implement allowing facilities to respond quickly to changing supply demands.

When a comparison is drawn against stainless steel, the benefits of single-use technology are numerous. They include lower capital cost, greater flexibility, lower environmental impact as well as more efficient and quicker manufacturing practices.

Single-use technology adoption has led to reductions in capital investment by as much as 25–30% in some cases and increased speed to market by as much as 60%…Read the full article in Manufacturing Chemist here.

To read more about the GE Single Use offering get redirected to the GE Lifesciences website here.

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